August is Psoriasis Awareness Month. Psoriasis affects an estimated 125 million people worldwide. It is an immune system disorder in which white blood cells, known as T cells, mistakenly attack skin cells, which causes the skin-cell production process to go into overdrive. This results in a build-up of skin cells causing red, scaly patches on the skin. This manifestation is a sign of systematic inflammation and the condition has several comorbidities, including inflammatory bowel disease, arthritis, depression, cardiovascular disease and metabolic disease.
Five different types of psoriasis:
The exact cause of psoriasis is not known but research has found in those with a genetic predisposition for the disease, certain factors may trigger psoriasis. Common triggers include: infections (strep), weather (cold, dry conditions), injury to the skin, stress, smoking, heavy alcohol consumption, and certain medications.
At present, there is no cure for psoriasis but there are several classes of medications designed to treat psoriatic symptoms, including topical ( e.g. Corticosteroids, Vitamin D analogues, Calcineurin inhibitors and cold tar), light (Sunlight, UVB, Psoralen plus ultraviolet A), and systemic therapies (e.g. Cyclosporine and Methotrexate). In the last decade biologic drugs (e.g. etanercept (Enbrel), infliximab (Remicade), adalimumab (Humira), ustekinumab (Stelara)) have been developed for autoimmune disorders including psoriasis. These drugs have proven to be highly effective for those suffering with moderate to severe psoriasis. However, they are costly and not always covered by health insurers or national health systems. The development of biosimilars of these blockbuster drugs has the potential to dramatically reduce costs and increase access for the millions of individuals with psoriasis across the globe.
Cromos Pharma has a strong track record in managing clinical trials designed to find effective treatments for psoriasis and wide-ranging expertise in dermatology and rheumatology studies. Read our Psoriasis Case Study here.
Cromos Pharma is delighted to be taking part in the upcoming DIA Europe conference (15 – 19 March 2021) and BIO-Europe Spring (22-25 March 2021).
February 11th is International Women and Girls in Science Day. A joint UNESCO and UN-Women initiative, it aims to promote the role of #WomenInScience and to challenge some of the barriers to girls pursuing a career in science.
Are you a sponsor seeking to conduct clinical trials in the European Union but do not have a registered office in the European Economic Area? If so, in order to comply with the European Union Clinical Trial Directive, you are required to work with a Legal Representative registered in an EEA country.
Each 4th February, #WorldCancerDay aims to raise awareness of the global personal, social and economic burden of cancer. World Cancer Day was established in Paris at the first World Cancer Summit in 2000.
As 2021 begins, many countries are grappling with a renewed surge of COVID-19 infections necessitating further public health restrictions putting more pressure on health systems, societies and global economies. The task of rolling out approved vaccines is increasingly urgent. Almost 16 million doses of COVID-19 vaccines have been administered to date in 37 countries worldwide according to data compiled by Bloomberg ( updated 7 Jan 2021).
Tuesday 1 December marked World AIDS Day 2020. Although throughout this year our focus has been on the coronavirus pandemic, World AIDS Day is an opportunity to reflect on another pandemic where a virus passed from animals to humans with devastating consequences. To date 77 million people worldwide have been infected with HIV. In spite of innovative new treatments 35 million people have died from the virus.
If you missed the live webinar “Where in the world should I locate my pivotal clinical trial?” you can now watch the recording by clicking here. The webinar hosted by the Society of Physician Entrepreneurs (SoPE) and Workforce Genetics features Cromos Pharma's CEO Vlad Bogin, M.D, FACP.