Cromos Pharma Your Rescue CRO

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When trials faulter, we deliver

Trusted by Sponsors Across 20+ Countries to Rescue and Relaunch Stalled Trials

Whether you’re facing recruitment delays, regulatory setbacks, or site underperformance, we restore momentum — fast.

Expert Support to Get Your Trial Back on Track

Intervening Early is the Difference Between Recovery and Regret

Regulatory delays, recruitment failure, poor site performance — we know what puts trials at risk. Cromos Pharma offers proven rescue capabilities, combining rapid assessment with senior-level intervention to get your trial back on track — and keep it there.

We Support Rescue Studies by

80+

Rescue trials supported across multiple therapeutic areas, from Phase I to Phase III

8 weeks

Average time to relaunch after rescue initiation

92%

On-time study completion rate after Cromos Pharma intervention

Global Reach, Local Expertise

Active operations in the US, EU, CEE, Türkiye, and Central Asia

We Support Rescue Studies by

Diagnosing root causes

Stabilizing operations

Rebuilding study momentum

Our 3-stage Rescue Study Strategy

We follow a structured yet flexible process regain control of your trial and ensure long-term recovery quickly.

Stage 1 — Root Cause & Rescue Blueprint

  • Assess trial performance across recruitment,
    sites, vendors, protocol, and logistics
  • Conduct updates feasibility assessments and review recruitment bottlenecks 
  • Engage all stakeholders to align on priorities
  • Build a tailored rescue roadmap with timelines, resources, and metrics

Stage 2 — Stabilization & Relaunch

  • Rework or amend protocols and submissions as needed
  • Re-engage, retrain, or replace underperforming sites and vendors
  • Deploy optimized processes across all operational layers
  • Roll out optimized processes across all touchpoints
  • Implement real-time data oversight and risk management

Stage 3 — Delivery & Closeout

  • Query resolution and data cleaning
  • Medical review and listing reconciliation
  • Database lock and final TLFs
  • Clinical study report, submission-ready datasets, and eCTD support
  • Transparency package, publication support,
    and knowledge transfer to your team

Why Leading Sponsors Choose Cromos for Clinical Trial Rescue

We understand that when sponsors seek a rescue CRO, they require speed, clarity, and a senior-level commitment. Here’s why leading biotechs and pharma companies turn to us when trials go off track:

Fast, Strategic Turnaround

Operational and strategic gaps are identified quickly and addressed without delay.

Tailored Rescue Strategies

Each clinical trial rescue plan is approached with fresh diagnostics and a custom intervention strategy.

Senior Leadership on Every Project

Rescue projects are overseen by experienced leadership — no handoffs to junior staff.

Cost-Conscious, Outcome-Focused

We work within your budget and timelines to deliver success without excess overhead.

Accelerated Recruitment Solutions

We complement rescue services with targeted digital patient recruitment strategies — accelerating enrollment through data-driven campaigns and real-time lead tracking

Transparent Communication and Oversight

You stay informed at every step, with regular check-ins, clear reporting, and real-time visibility into progress.

Case Study: From Lagging Enrollment
to Completion Ahead of Target
A Phase III Study in Metastatic Castration-Resistant
Prostate Cancer

Before Cromos:

  • Trial stalled with just 150 of 1008 patients enrolled across 19 countries
  • Sponsor facing significant timeline risk

Cromos Pharma’s approach:

  • Assessed current status:
    • Inclusion/exclusion criteria
    • Reasons for screen failures and underperformance
  • Conducted detailed feasibility assessment in potential new venues
  • Consulted with new Key Opinion Leaders and PIs
  • Recommended to the Sponsor to expand the trial to 5 Central and Eastern European countries

Results:

  • Total global enrollment of 1008 was reached in 39 months
  • Cromos Pharma’s enrollment of 392 patients (40% of total population) was reached in 27 months.
Study metrics:
Trial Overall
24 countries
39 months
1008 patients
1.1 patients per country
per month
Lead CRO*
19 countries
39 months
616 patients
0.8 patients per country
per month
Cromos Pharma
5 countries
27 months
392 patients
2.9 patients per country
per month
*Additional benefit: Cromos’s competitive enrollment success also improved the performance of the Lead CRO by > 35%
Metrics by countries:
Bulgaria
5 sites
37 patients
Czech Republic
11 sites
72 patients
Hungary
4 sites
58 patients
Poland
9 sites
161 patients
Slovakia
3 sites
64 patients

Cromos Pharma stepped in at a critical moment and made an immediate difference. Their team was proactive, responsive, and delivered exactly what we needed to get the study over the finish line. We’re grateful for their partnership.

VP, Clinical Operations Mid-Size Biotech

Getting Your Trial Back on Track Together

At Cromos Pharma, we work side-by-side with sponsors to overcome challenges and keep studies moving forward.

Our team will partner with you to understand your trial’s unique needs, identify the root causes of any setbacks, and implement a practical, targeted recovery plan. 

From recruitment acceleration to site performance optimization, we focus on solutions that align with your priorities and set your study up for success.

Book a Free Consultation