Advancing Clinical Trial Diversity: A Step Towards Equitable Healthcare The lack of diversity in clinical trials has long been a concern, leading to adverse side effects and health disparities among various racial and ethnic groups, as well as women. Historically, clinical trials have disproportionately included white men as participants, which limited our understanding of how drugs and treatments affect different populations. This article explores Read more
Clinical Trials in the Czech Republic: A Prominent Hub for Scientific Discovery and Cost Optimization The Czech Republic has emerged as an attractive destination for clinical trials, offering a strong infrastructure, supportive regulatory environment, and ethical standards. This article provides a detailed exploration of the country’s scientific and logistical advantages, highlighting its cost- and time-saving potential. Additionally, the article presents a country overview, demographics, healthcare system, and the reasons why the Czech Read more
Addressing the Underrepresentation of Older Adults in Cancer CT: Advancing Inclusion for Improved Care The underrepresentation of older patients in cancer clinical trials poses a significant concern as it limits the generalizability of trial results to the broader population, particularly older adults who are affected by cancer more frequently. Various factors contribute to the exclusion of older participants, including age-related eligibility criteria, preexisting conditions, polypharmacy, functional limitations, and exclusion Read more
Regulatory Focus Shifts: Expanding Role of Real-World Evidence for Evaluating New and Expanded Drug Indications In the ever-evolving landscape of healthcare, real-world evidence (RWE) is attracting growing interest from regulators as a valuable source of information for evaluating new and expanded drug indications. RWE refers to data collected from healthcare claims, registries, electronic health records and even non-traditional sources like mobile phones, consumer devices, and various tools used for telehealth. Read more
