Clinical Research Focus. 58th Edition

AstraZeneca and Oracle Partner to Transform Clinical Trial Recruitment with AI 

AstraZeneca and Oracle have announced a new collaboration to explore how AI and real-world data can improve patient identification, accelerate clinical trial recruitment, and optimize study operations. The initiative aims to connect clinical research with everyday healthcare, potentially helping sponsors overcome one of the industry’s biggest challenges: finding and enrolling eligible patients. 

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Smarter Clinical Trial Budgeting Starts Here 

Six months ago, Cromos Pharma launched its free AI-powered Clinical Trial Budget Calculator to simplify early-stage study planning. Since then, we’ve received positive feedback from users who value its speed, flexibility, and ability to turn complex budgeting into clear, actionable estimates. Explore how the tool helps sponsors estimate study costs, compare scenarios, and make more informed planning decisions in minutes. 

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FDA Approves Immunotherapy That Could Help Rectal Cancer Patients Avoid Surgery 

In a major breakthrough in oncology, the FDA has granted accelerated approval to Jemperli (dostarlimab) for certain patients with locally advanced rectal cancer. Clinical trial results showed that nearly 75% of patients avoided chemotherapy, radiation, and surgery after more than two years of median follow-up, highlighting the potential of immunotherapy to transform cancer treatment. 

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AI in Clinical Trials: Who Is Accountable for Quality? 

As AI becomes more integrated into clinical research, quality leaders face new challenges around validation, oversight, and accountability. In this article, Joris De Maeseneire, Head of Quality at Cromos Pharma, shares his expert perspective on six essential questions every quality leader should ask to ensure responsible AI adoption while protecting patient safety and data integrity. 

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EMA Recommends New Treatment for Metastatic Pancreatic Cancer 

In a significant development for oncology, the European Medicines Agency (EMA) has recommended the authorisation of Rasonque for metastatic pancreatic cancer, a disease with limited treatment options and a high unmet medical need. The medicine underwent a rolling review, highlighting how accelerated regulatory pathways can help bring promising therapies closer to patients. 

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Clinical Trials in Italy: A 2026 Guide to Patient Recruitment, Regulatory Approval, and Study Start-Up 

Italy remains a key destination for clinical research in Europe, with growing trial activity, strong oncology expertise, and new initiatives to accelerate regulatory approvals. In our latest article, we explore the country’s clinical trial landscape, key regulatory developments in 2026, patient recruitment opportunities, and practical considerations for sponsors planning studies in Italy. 

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Breakthrough in Cancer Immunotherapy: Precision T-Cell Therapy Shows Promise Against Treatment-Resistant Tumors 

An experimental immunotherapy called invika has shown promising results in a clinical trial involving patients with treatment-resistant cancers. By selectively stimulating tumor-fighting T cells, the therapy demonstrated the potential to halt disease progression in some patients, offering a promising new approach for cancers that no longer respond to conventional treatments. 

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Biopharma R&D in 2026: 7 Numbers Every Sponsor Should Know 

The biopharma R&D landscape continues to evolve, bringing new opportunities and challenges for clinical development. In our latest article, we highlight seven key numbers shaping the industry in 2026 and explore what they mean for clinical trial sponsors, from investment trends to development strategies and operational priorities. 

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New Data Platform Aims to Improve Clinical Trial Site Performance 

The Society for Clinical Research Sites (SCRS) has launched the Eagle Insights Dashboard, a new data intelligence platform designed to help sponsors and CROs evaluate and strengthen their relationships with clinical trial sites. Using verified site feedback and industry benchmarks, the platform helps organizations identify performance gaps, improve collaboration, and make more informed operational decisions. 

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